PLO: Raising in early position pre-flop?

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Likewise. I find that unless you're playing with the same small group of players all the time, unknowns will invariably put you on high cards/big pairs from EP. If you're doing it with rundown hands (4567 or 5689 etc) and you flop gin, you will get paid off by two pair a lot of the time purely as the villian is trying to crack what he perceives as AAxx.

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There is nothing more fun than raising in EP w 8765 and taking it down on an A92 flop.

If you limp and hit the flop you will usually not be paid off by players with marginal hands like bottom two pair you would have stacked if you had raised preflop.

If you are playing regularly with decent players you need to include these types of hands in your range or not raise in EP at all.