Can anyone help me??!?!?! hard drive filling up constantly

[TheWorm967]

hello i'm on windows Xp and my hard drive recently filled up overnight with no major downloads made, also when i delete something to free up space it has little to no effect and just fills up again? has anyone had this problem? I've run every concievable virus/spyarwe/registry cleaner everything and it has revelaled nothing. Any computer genius care to tackle this one? any help would be greatly appreciated