Baseball situation question - 2nd base nobody out vs 3rd base one out?

[posnera]

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It does depend, to some extent on the batter (and the speed of the runner), but in general, do you think it is a good play to sac bunt with nobody out and a runner on second?

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This isn't what I was referring to when I said it depends.

Unless you are very late in the game and tied(and sometimes down by 1), it is nearly always a horrible play sac bunting.

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I disagree. Maybe the best way of framing the question is - In which situation are you more likely to score?

I think you are more likely to score from second with no outs, so even in the bottom of the ninth, down by one, bunting is a generally bad play.