Game theory and bluffing question

[rufus]

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In general, you want the ratio between your bluffs and your legitimate bets to be about the same as the ratio between 1 bet and the pot size. This is so that your opponent can not profit - you are indifferent as to whether he folds or calls.

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Situations that are earlier in the game - that is with more potential betting, or cards to come - will probably have significantly different ratios since those will reduce the effective value of a good call down. (You'll see that most discussion of game-theory bluffing deals with the river or an analogue where there are no more betting rounds or cards to come.)