please move to microlimit ?

[rafiki]

Find myself asking a question that may be noobish, but my recent return to short handed has me questioning some strategy. the question is:

I have a 25/20 type player in the cutoff of a 6max online game. When all fold to him in the cutoff and he raises, what's the lowest range of hands I 3ball ? Let's assume that the blinds are tight enough to fold garbage and the play is designed to isolate against him.

His range is 22-AA, any broadway of any kind, most aces, probably suited connectors as low as 56s and one gappers as low as 97s.

I'm not really good enough with the mathematical distributions to figure out what weaker hands I 3bet here. Someone want to take a shot ? Is it mostly determined by who the better player is post flop ?