NL25 when c-bets don´t work (theory)

[WantToLearn]

Ok, so I still suck when playing against gamblers.
The game is NL25. In theory, a table w/ HUGE average pot and HIGH flop seen rates is a dream. In practice, I feel confused when my usual c-bets don´t work at all.

Say we are at a table where every normal sized preflop raise gets 3 callers or more. A flop c-bet never takes it down. As for big river bets, big bets and big calls usualy mean big hands. They are loose when they enter, but they need some kind of real hand to get stacked. So, money must be there to be made after turn card comes but before showdown, right? Second-barreling the turn w/ air often is probably sort of +EV w/ ultra high variance.

So, what´s our <u>preflop play</u> with:
1. small and middlish pocket pairs, early and middle position, first in or one limper before us?
2. AQ in middle position first in, or one limper before us?

Again, lots of callers are to be expected and a flop c-bet doesn´t win the pot.

Thank you!