Defending a Good Flop

[Max1]

Okay, you're sitting on a mid pair that catches a set on the flop. There are 2 or 3 players in, but there are two cards to a straight or flush draw on the board. You want to max your payoff, but are vulnerable to being outdrawn. I know there are a lot of details left out like position, preflop action, etc. but is there a general strategy out here...