When is it right to play AXs

[RileyB1]

so i couldent find any threds on this when i looked so ill just ask it here.

when is it right to play AXs in limit?

im sure this answer differes on the situation like A9s should be an open raise in late position (right?). one question is can you limp A2s from UTG and UTG+1 in a passive game? then dump if you dont hit the flush draw?

is AXs only a good play from late position, or should you only play if you have 4+ players for 2 or less bets?

im sure the first answer ill get is "it depends" and i understand that. but im still a big time looser and cant find my leaks or improve my play so im asking for some guideance.

i ask because im looking at my OP stats and cant figure out why im a net loss -0.04/hand on my AKs (20 actual hands) and a winner of 0.03/hand with A4s (22 actual hands)(after ~8500 ahnds)

hope the question is clear.
-Riley