What line to take in what spot?

[gergery]

I'm interested in others views on when you should come alive and start raising in a hand. For example:

Higher stakes game fullring Limit O8, opponents are not terrible not great but are fairly aggressive. You open limp in with a somewhat speculative hand in MP. Button raises, only BB and you call. You catch a strong likely best but not monster hand on flop, and know Button will cbet and BB will likely call. My questions are:

How do you decide between different lines to take:
- lead/3bet flop
- c/r flop lead turn
- flat call flop, c-r turn
etc.

In other words, while all are something you consider, what MOST influences your decision:
- Flop texture
- aggressiveness of opponent
- villain range
- hand they put you on
- how multiway/drawy your hand is
etc.

If it helps to make this concrete, lets say your hand is
1) 245Qds and flop is 34Q with two of your suit to the 5
2) A489s and flop is A89 twoflush in suit you don't have

sorry if this is vague, I'm trying to understand different thought processes on when to start jamming

-g