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This thread discusses some aspects of PLO play.
As far as starting hands, your range varies upon position and opponents.
Play cards that are connected such as jt98, a876.
Suited hands have considerable extra value. So jt97 ds has more value than qjt9 unsuited.
Raise with a variety of hands preflop, not just aaxx.
The general forum line is VPIP around 35-40.