I have not seen this Pick-up Artist show, but for anyone interested in how Mystery does his thing go pick up a copy of
The Game by Neil Strauss. It's basically a book about how to pickup girls, as taught by Mystery to the author of the book. From friends I know who practice the book's content religiously, all the negative game and pickup scenarios that Mystery teaches work very well on girls that are seemingly out of their league.
For lots of entertainment value, give a hot and intelligent female friend a copy of this book to read, go to a bar with her, and watch as some poor shmuck inevitably tries an approach from the book on her before she finishes the approach for him...line for line.