[Aviston]

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QTip, the best gauge for how big or small a pot is, is SPR. It basically tells you in one number.

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With regards to SPR, at what SPR would a pot begin to be considered "big"?

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Let me clarify:

Actually, The Commitment Threshold is the big tool you can use to gauge if you're getting into a big pot. (I.e. - Pot is one-fourth of the remaining money.) SPR is a great gauge at the start of the flop. (And If you have an SPR of 4 you are at the threshold.) But you'll still need to be aware of the commitment threshold (and general stack/pot considerations) on later streets.

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Alright, so a effective stack to pot ratio of 4 would indicate the threshold and be entering, generally, into big pot territory (I did not use SPR specifically because you have reserved its use at the final preflop pot only).