One I tend to play on a regular basis is Melon Ball. The game generally is more effective when people are drinking beer or less alcohol per drink beverages as otherwise it can potentially get out of hand.
One person Deals as goes around clockwise with 4 rounds.
Round one: Dealer ask player red or black and flips over a card to player after guess. If player is correct they can give 2 drinks to anyone they choose, if wrong they drink 2.
Round Two: Dealer asks player higher/lower then the card infront of them(IE red/back card). If correct give 4 drinks, wrong take 4.
Round Three: Dealer then asks players whether it will be inbetween the two cards infront of them(IE red/back and high/low card). Give 6 if correct take if wrong.
Round Four: Players have to guess the suit of the next card, if wrong take 8 give if correct.
By this point players should all have 4 cards infront of them. So it's time for the melon ball round, which I'm going to try and use MSPaint for an assit here. You lay out cards face down in this manner. Cards on the right are Give cards(10drinks), Left are take cards(10 drinks) and the two horizontal in the middle are the melon balls(AKA finish your drink).
Basicly you flip over the a card on the right side and if any of the four cards you still have infront of you match, you get to give drinks. Ex. You have 4c 5h Ac 3s and the first card on the right is a 4h you get to give 10 drinks. and vice versa for the take side. After alternating between the give/takes side you proceed to the melon balls. When said card is flipped over whomever has a matching card must finish their drink(Doesn't matter if it's mostly empty or just opened, they just have to finish the current drink) Ex. If Jane has Kc, Kh, 3c, 6c and the top horizontal card is the Ks, then Jane must finish the current drink + another whole drink. Rinse and repeat till you can't stand.