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Old 06-04-2006, 01:38 PM
posnera posnera is offline
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Join Date: Jan 2006
Posts: 874
Default Re: Alcohol Bypassing the Liver?

Well, the anatomy is correct:

The veins that receive blood from the end of the colon do not drain into the portal vein, which leads to the liver. They go directly into the inferior vena cava which bypasses the liver and goes directly to the heart. This avoids what is known as "first-pass metabolism." This should result in higher venous blood alcohol concentrations than if the alcohol is absorbed directly from the small intestine.

However, alcohol is volatile and can be excreted by exhalation in the lungs. The venous blood from the IVC passes through the right side of the heart to the lungs. A higher venous concentration of alcohol would result in more alcohol being excreted by the lungs, so the arterial blood alcohol content (which is the important one) would be lower than the venous. This probably wouldn't have a huge effect.


And, the entire blood volume circulates in about 1 minute. So the liver will eventually be given a chance to metabolize the alcohol that you have cleverly shoved up your ass.
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