They already have an approximate game theoretical solution to the limit hold em heads up player .
http://www.cs.ualberta.ca/~games/pok...hanson.msc.pdf
The University of Alberta has come up with "Spartan" which plays a tough game of limit hold em . After several thousand hands played , I'm slightly on the negative side and I consider myself to be a strong heads up player .
On the other hand , I can beat the nl hold em bots without looking at my cards; well , almost . There is a lot more work to be done for the nl hold em bots but I'm certain within a few years , the AI's will be able to compete with the upper echelon of players .