[pzhon]

If you feel you have a significant advantage playing PLO $10 (and the play at that level is generally terrible--people can't read the board at PLO $25), then you don't need to move down. You don't need 25 buy-ins to take a shot at a soft game, and you shouldn't move down from a soft game just because you drop to 25 buy-ins.

You may hear that people recommend having a huge number of buy-ins in Omaha. However, that advice is for tougher games which can't be beaten for nearly the same rate. Large downswings are much more common in games where you are playing better opponents. Even when someone calls on a weak draw when a better opponent would not have gotten involved, playing that pot is usually much safer than normal poker, which means it decreases the bankroll you need.