[Potvaliant]

I'd add Benicio Del Toro, Tobey Maguire, and Philip Seymour Hoffman; I'd probably throw John Tuturro in there too, except for his unfortunate habit of saying yes to Adam Sandler.

But overall, my first pick would have to be ... Bill Murray. A few genuinely crappy movies, a few misfires, and a ton of great or near-great or at least good, interesting movies.