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Has anyone ever had problems in mid air?
Anyway this article is encouraging.
Flying aticle
It appears that all modern planes can operate normally on one engine so if something goes wrong mid air you should be fine and if all the engines fail at crusing altitude you are still likely to be fine b/c the plane can glide to safety. They have a 85 mile gliding range if both engines die at 35K feet which is comforting to know b/c I always thought they go into divebomb mode if they lose power. It seems the main problem is when they lose power during takeoff or landing.
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Planes throttle down the engines a great deal when they are like 50-100 miles away from the destination airport to conserve fuel.