I have played poker with sound regognition for some time now and I say it is really cool.
My reason for using sound was originally my severe tennis elbow witch prohibitet me using computer.
I use glovepie, it is keyboard/gamepad/wiimote/microphone emulator.
Very easy to use and best it is free
http://carl.kenner.googlepages.com/glovepie_download
You also need sound regonition software installed in your computer, it is also free
http://www.chant.net/downloads/sapi51.exe
It is preferred if you train your computer to understand your speech, you'll find that in control panel.
And if you want to replace your mouse to wiimote, you can also use glovepie with that. You need (preferable bluesoleil) bluetooth device, there was somewhere link in working devices. I haven't tried wiimote yet.
Maybe someone of you want to play poker with wiimote. What I have read about it it is not very diffucult, I'm just too lazy to test it.
Note that you can also use it emulate gamepad
Only real problem is that glovepie needs hotkeys(like f1,f2,ect.). Many site doesn't have hotkeys so AKH is only real option to use with it, or maybe I can use already made gamepad conficuration, don't know yet...