[Dire]

The environment is great for big daddies. Bunch up alot of explodable barrels/tubes and get him to chase you to the spot then add a bit of fire, or attack one big daddy and hide behind another and get them to attack each other. I've heard (but not tried myself) that you're able to even attach proximity mines to items. Explosive barrel + 6 proximity mines + telekenesis would be nice. Just stuff like that. There's alot of ways to take them down.