[Eddi]

I know the read is impossible to make, which is why this is a general question and not a specific hand one.

What about fold equity? Seems like you're assuming we have none.

So if you magically DO know your opponent has a pair and he 3-bets, do you fold, reraise(AI?) or call with AK?

It seems to me calling is the worst choice since you'll hit your pair only in 1/3 of the cases on flop and will have to fold to the CB + if you DO hit your pair, it's unlikely you'll get much more than the CB out of your opponent. So I'd rephrase the question - do you fold or do you 4-bet/4bAI? Do your actions change with AKo vs AKs and also OOP vs IP?