[Dire]

[ QUOTE ]
You can choose to respawn instead of reload save games, and the enemies will have the same damage as when you died. If you don't want this, just load save games like any normal game and it's just as difficult, this is what I'm doing.

[/ QUOTE ]

Ditto here. At least on hard for sure, I think the vita-chambers should have been disabled or had some serious penalty like 40 ADAM. But it's easy to play like they don't exist and their existance probably does make the game accessible to more players.