[SweetLuckyMe]

Depends on how much of a caller they are. If you know you're not getting anyone to fold, then don't bet if you're not sure that you have more than your share of pot equity. If you think you'll get one to fold then bet if you have a potential 2-way hand (preferably the current best high hand). Keep in mind that betting is always better than check-calling, so if you have a hand that you'd call if someone else bet, then bet out yourself. Give good things a chance to happen.

Another decent strategy is checking with the intention of check-raising if you check, the next guy checks and the last guy bets - this will virtually guarantee you get rid of the guy in the middle with your check-raise. Just be wary of those calling station fish who tend to limp in with a lot of brick pair hands - since you're putting a lot of chips into a small pot, you don't want to find you're way behind up against a pair of tens. This play is best against the tighter players who will fold when they brick 4th (and never call a bet or check-raise in a small pot without a premium hand).

Another more conservative way is to try to guestimate the hands where you have more than 33% in pot equity vs. their likely current holdings and bet when you do and check/fold when you don't. (i.e. you have Ace, 8, baby, rag and they have 2, 3, 7, K and a king is dead, then you're well ahead, so a bet is in order)

It depends so much on how your opponents play - that's the biggest factor.