[dylan's alias]

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But science, and scientifically inclinded folk are far more comfortable with an end result of "dunno" than most.

Obviously a drive for exploration is great. It's when that bricks out that I see mistakes being made. Obviously religion is the best example. (warning, crude, inartful example follows) We cannot rationalize how we got here, etc, so some folks made up a Unicorn in the sky to help them get through the day.

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IMO, if science and scientfically minded people, start getting comfortable with an end result of "dunno" when things start to brick out, I think humans as a whole, are going to start to suffer. I personally believe that science has progressed due to the simple fact that there are certain people who refuse to accept the "dunno".

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That's not the point. Science can accept "dunno". It is critical to the process that there be an unknown or an unsatisfying answer to a question. This may drive them to probe the question further, think more deeply about it, and try to test their new concepts. Science does not allow unproven or unprovable concepts to become truth.