[astroglide]

[ QUOTE ]
The thing is this stuff is incredibly difficult to quantify and analyze with any sort of resolution. Realise that 100 calories is a little more than a single egg or a glass of orange juice. Actually tracking caloric input/output at that sort of resolution is practically impossible.

[/ QUOTE ]

i would think that it could be analyzed pretty well with test mammals. they're often inbred for similarity, etc and the calorie stuff could still be scaled out for at least an attempt at an extrapolated human analog. it's gotta be tough to get normal people to commit to 6 month+ studies like this just because the control conditions and upkeep are a lot. but it's just really surprising to me in general how there are so many accepted truths, like not eating before bedtime, that are basically more associated with magazines than studies. however true or at least logical-sounding, it still blurs the line between science and hearsay.