[jjshabado]

Buffalo is definitely the best bet if you're flying from the States (which I'm assuming you are by the use of "up there"). You avoid annoying international flight details, its cheaper, and its closest. I think this is definitely your best option. I've never flown into Buffalo so I can't help you with how you get to the casino.

Another possibility is flying to Hamilton which I've done a couple of times. Its a small airport, and you'd probably have to rent a car, but its an option and has some cheap carriers that run flights there.