[ohnonotthat]

If your opponents call big bets far more often than they should you can play Ax/s but play it for the minimum.

If your opponents fold to big bets far more often than they should you can play (obviously your approach to the hand will be opposite of above).

If your opponents play reasonably well these hands have little value anywhere other than on or near the button.

If you play extremely well relative to the opponents at any particular table you will give up almost nothing if you play alot of hands preflop for the minimum; it's post-flop where these [questionable] hands get expensive.

- Others can give you much more detailed advice; this was an "in case nobody else responds" answer.