[Slim Pickens]

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Does that mean we're supposed to refrigerate all the unused portion and then re-microwave it next time, repeatedly microwaving the entire jar forever? Or it it assumed that we're going to use the entire jar in one shot if we heat the entire jar?

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Re-microwave as necessary. There's not much you can do to destroy artificial hot fudge sauce without tactical nuclear warheads.

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And what about if it's a plastic bottle instead of a glass jar? Won't the evil microwave rays plus plastic eventually kill you?

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...not unless you're a parakeet. I wouldn't nuke it until the plastic starts melting and then spoon the hot gooey goodness straight into your mouth though.