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But science, and scientifically inclinded folk are far more comfortable with an end result of "dunno" than most.

Obviously a drive for exploration is great. It's when that bricks out that I see mistakes being made. Obviously religion is the best example. (warning, crude, inartful example follows) We cannot rationalize how we got here, etc, so some folks made up a Unicorn in the sky to help them get through the day.

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IMO, if science and scientfically minded people, start getting comfortable with an end result of "dunno" when things start to brick out, I think humans as a whole, are going to start to suffer. I personally believe that science has progressed due to the simple fact that there are certain people who refuse to accept the "dunno".