[Harv72b]

I would think that your basic strategy shouldn't change, you just have to factor in the $12 river bets/raises when calculating your implied odds on draws. And of course factor that into your reverse implied odds when you're holding a borderline made hand on a drawy board or drawing at a low flush or non-nut straight in a multiway pot.

Basically, just understand that you're going to make up twice as many BBs when you hit on the river as you would in a normal 3/6 game, but that you can also lose twice as many when you river your way into a hand over hand situation. Maybe you could justify trying the odd river bluff in a HU pot if you think the other guy is playing scared.