[hawkeye]

The problem I see with running around or kicking / flailing your legs is the potential for one of the little carcasses strewn about the room to get caught up in your legs. Inevitably, when this happens, the likelihood of a serious ACL or MCL injury is increased.

To avoid this undesirable situation I would most likely fight my way to an edge of the room, and essentially back up near a wall. By doing this I could guarantee that none of the buggers could get behind me and cause damage to my knees. Also, the proximity to the wall would afford you the opportunity to bash the anklebiters' heads against the wall one at a time until they are neutralized.